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Group II (n 7) underwent placement of a reservoir as above, and received repeated infusions of 5 x 106 normal rat hepatocytes in 3 ml of saline on the same days.

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In vivo proton magnetic resonance spectroscopy of human spinal mass lesions. Microarrays can also be used to study the mechanism of drug action and drug metabolism by examining the effect of drugs on host gene expressions (4). Also gain-of-function mutations in RASRAF signal- ing, involving several loci, seem to be involved in the hypertrophic cardiomyopathy in both Noonan and LEOPARD syndromes (Pandit B et al 2007 Nature Genet 39:1007; Razzaque MR et al 2007 Nature Genet 39:1013).

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